A cephalosporin bearing (1-methylpyrrolidinium-1-yl)methyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton.
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This entity has been manually annotated by the ChEBI Team.
A semi-synthetic fourth-generation cephalosporin antibiotic, cefepime shows greater activity than third-generation agents against both Gram-positive and Gram-negative organisms, and is used as its hydrochloride salt for treatment of severe nosocomial pneumonia, infections caused by multi-resistant microorganisms (e.g. Pseudomonas aeruginosa) and empirical treatment of febrile neutropenia.