CHEBI:132973 - Zepatier

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ChEBI Name Zepatier ChEBI ID CHEBI:132973 Definition A two-drug mixture consisting of elbasvir, a hepatitis C virus (HCV) NS5A inhibitor, and grazoprevir, an HCV NS3/4A protease inhibitor, and is indicated for treatment of chronic HCV genotypes 1 or 4 infection in adults. Stars This entity has been manually annotated by the ChEBI Team. Roles Classification Biological Role(s): antiviral drug A substance used in the prophylaxis or therapy of virus diseases. Application(s): antiviral drug A substance used in the prophylaxis or therapy of virus diseases. hepatoprotective agent Any compound that is able to prevent damage to the liver. View more via ChEBI Ontology ChEBI Ontology Outgoing Zepatier (CHEBI:132973) has part elbasvir (CHEBI:132967) Zepatier (CHEBI:132973) has part grazoprevir (CHEBI:132975) Zepatier (CHEBI:132973) has role antiviral drug (CHEBI:36044) Zepatier (CHEBI:132973) has role hepatoprotective agent (CHEBI:62868) Zepatier (CHEBI:132973) is a mixture (CHEBI:60004) Synonyms Sources Elbasvir and grazoprevir ChemIDplus Elbasvir mixture with grazoprevir ChemIDplus Elbasvir-grazoprevir mixt KEGG DRUG Elbasvir/grazoprevir ChemIDplus Brand Name Source Zepatier KEGG DRUG Manual Xref Database D10778 KEGG DRUG View more database links Citations Types Sources 26849059 PubMed citation Europe PMC 26938699 PubMed citation Europe PMC 26943930 PubMed citation Europe PMC 27091555 PubMed citation Europe PMC 27403342 PubMed citation Europe PMC Last Modified 11 August 2016

General Comment 2016-08-10 This mixture has a ChemIDplus substance accession number S900006960