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M  END
> <ID>
CHEBI:173086

> <NAME>
ferrostatin-1

> <DEFINITION>
An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals.

> <STAR>
3

> <SYNONYM>
ferrrostatin 1; Fer-1; 3-amino-4-cyclohexylaminobenzoic acid ethyl ester

> <IUPAC_NAME>
ethyl 3-amino-4-(cyclohexylamino)benzoate

> <FORMULA>
C15H22N2O2

> <MASS>
262.353

> <MONOISOTOPIC_MASS>
262.16813

> <CHARGE>
0

> <SMILES>
CCOC(=O)C1=CC(N)=C(NC2CCCCC2)C=C1

> <INCHI>
InChI=1S/C15H22N2O2/c1-2-19-15(18)11-8-9-14(13(16)10-11)17-12-6-4-3-5-7-12/h8-10,12,17H,2-7,16H2,1H3

> <INCHIKEY>
UJHBVMHOBZBWMX-UHFFFAOYSA-N

> <CAS_REGISTRY_NUMBER>
347174-05-4

> <PUBMED_CITATION>
22632970; 26385697; 26410073; 26696014; 28250973; 28386601; 28783875; 30354101; 31531196; 31571665; 31574461; 31864943; 32161620; 32984038; 33109343; 33126055; 33278745; 33464146; 33631670; 33669598; 33991524

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