Ketcher 04041717022D 1   1.00000     0.00000     0

  0  0  0     0  0            999 V2000
M  END> <ID>
CHEBI:94373

> <NAME>
mosapride

> <DEFINITION>
A racemate comprising equimolar amounts of (R)- and (S)-mosapride. It is a gastroprokinetic agent which acts on 5-hydroxytryptamine type 4 (5-HT4) receptors in the gastrointestinal plexus, consequently increasing the release of acetylcholine and hence enhancing gastrointestinal motility and gastric emptying.

> <STAR>
3

> <SYNONYM>
racemic mosapride; rac-mosapride; (RS)-mosapride; (+-)-mosapride; (+-)-4-amino-5-chloro-2-ethoxy-N-((4-(p-fluorobenzyl)-2-morpholinyl)methyl)benzamide

> <INN>
mosapridum; mosapride; mosapride; mosaprida

> <FORMULA>
C21H25ClFN3O3

> <MASS>
421.900

> <MONOISOTOPIC_MASS>
421.15685

> <CHARGE>
0

> <CAS_REGISTRY_NUMBER>
112885-41-3

> <CHEMIDPLUS>
112885-41-3

> <DRUGBANK_ACCESSION>
DB11675

> <KEGG_DRUG_ACCESSION>
D08236

> <LINCS_ACCESSION>
LSM-5042

> <WIKIPEDIA_ACCESSION>
Mosapride

> <PUBMED_CITATION>
2533479; 27561215; 28413522; 28587329; 28815345; 29399134; 29702482; 30526030; 30883253; 30897296; 31155551; 31318691; 31440072; 31496879; 31914075; 32235030; 32304239; 32825721; 33267769

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