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M  END
> <ID>
CHEBI:65585

> <NAME>
carnosic acid

> <DEFINITION>
An abietane diterpenoid that is abieta-8,11,13-triene substituted by hydroxy groups at positions 11 and 12 and a carboxy group at position 20. It is isolated from rosemary (Rosmarinus officinalis) and common sage (Salvia officinalis) and exhibits anti-angiogenic, antineoplastic, antioxidant and anti-HIV activity.

> <STAR>
3

> <SYNONYM>
Salvin; 11,12-dihydroxy-13-isopropylpodocarpa-8,11,13-trien-17-oic acid; (4aR,10aS)-5,6-dihydroxy-1,1-dimethyl-7-(propan-2-yl)-1,3,4,9,10,10a-hexahydrophenanthrene-4a(2H)-carboxylic acid

> <IUPAC_NAME>
11,12-dihydroxyabieta-8,11,13-trien-20-oic acid

> <FORMULA>
C20H28O4

> <MASS>
332.435

> <MONOISOTOPIC_MASS>
332.19876

> <CHARGE>
0

> <SMILES>
C1CC([C@]2([C@](C1)(C3=C(CC2)C=C(C(=C3O)O)C(C)C)C(=O)O)[H])(C)C

> <INCHI>
InChI=1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24)/t14-,20+/m0/s1

> <INCHIKEY>
QRYRORQUOLYVBU-VBKZILBWSA-N

> <CAS_REGISTRY_NUMBER>
3650-09-7

> <REAXYS_REGISTRY_NUMBER>
2707918

> <CHEMIDPLUS>
3650-09-7

> <METACYC_ACCESSION>
CPD-18103

> <WIKIPEDIA_ACCESSION>
Carnosic_acid

> <PUBMED_CITATION>
11504768; 17177234; 22232247; 22246562; 22687582; 22828666; 26976595; 27694001; 27703160; 27716981; 27957651; 28008719; 28159594; 28282784; 28288941; 28343998; 28440400; 28674855; 28877257; 28887507; 28916593; 28918123; 29100552; 8229021

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