Mrv0541 11121314442D          

 23 25  0  0  0  0            999 V2000
    3.7538   -4.7247    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7538   -5.5497    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4374   -4.3240    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.9995   -4.3240    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4374   -5.9975    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0
    2.9995   -5.9740    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1445   -4.7247    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.4374   -3.4754    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3395   -4.7247    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.1445   -5.5732    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    4.8145   -6.7047    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0131   -6.7047    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3395   -5.5497    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.8752   -4.3240    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.8752   -5.9740    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.6059   -4.7247    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    5.8752   -3.4754    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    7.3131   -4.3240    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3131   -3.4754    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    8.0674   -4.5597    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0
    8.0909   -3.2632    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.5859   -3.9232    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.4109   -3.9232    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  2  1  2  0  0  0  0
  3  1  1  0  0  0  0
  4  1  1  0  0  0  0
  5  2  1  0  0  0  0
  6  2  1  0  0  0  0
  7  3  2  0  0  0  0
  8  3  1  0  0  0  0
  9  4  2  0  0  0  0
 10  5  1  0  0  0  0
 11  5  2  0  0  0  0
 12  5  2  0  0  0  0
 13  6  2  0  0  0  0
 14  7  1  0  0  0  0
 10  7  1  0  0  0  0
 13  9  1  0  0  0  0
 15 10  1  0  0  0  0
 16 14  1  0  0  0  0
 17 14  2  0  0  0  0
 18 16  1  0  0  0  0
 19 18  2  0  0  0  0
 20 18  1  0  0  0  0
 21 19  1  0  0  0  0
 22 20  1  0  0  0  0
 22 21  2  0  0  0  0
 23 22  1  0  0  0  0
M  END
> <ID>
CHEBI:6741

> <NAME>
meloxicam

> <DEFINITION>
A benzothiazine that is piroxicam in which the pyridin-2-yl group is replaced by a 5-methyl-1,3-thiazol-2-yl group. A non-steroidal anti-inflammatory drug and selective inhibitor of COX-2, it is used particularly for the management of rheumatoid arthritis.

> <STAR>
3

> <SYNONYM>
UNII-VG2QF83CGL

> <IUPAC_NAME>
4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

> <INN>
meloxicamum; meloxicam; meloxicam; meloxicam

> <BRAND_NAME>
Mobic

> <FORMULA>
C14H13N3O4S2

> <MASS>
351.40100

> <MONOISOTOPIC_MASS>
351.03475

> <CHARGE>
0

> <SMILES>
CN1C(C(=O)Nc2ncc(C)s2)=C(O)c2ccccc2S1(=O)=O

> <INCHI>
InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)

> <INCHIKEY>
ZRVUJXDFFKFLMG-UHFFFAOYSA-N

> <CAS_REGISTRY_NUMBER>
71125-38-7

> <REAXYS_REGISTRY_NUMBER>
5886369

> <DRUGBANK_ACCESSION>
DB00814

> <KEGG_COMPOUND_ACCESSION>
C08169

> <KEGG_DRUG_ACCESSION>
D00969

> <PUBMED_CITATION>
10092958; 12387696; 16197363; 16623613; 16863437; 18405470; 19821429; 23306395; 23388116; 23406022; 24041211; 24084190; 28166217; 8882380; 9219316

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