Mrv0541 06191411032D          

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  1  2  1  0  0  0  0
  1  3  2  0  0  0  0
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  7  9  2  0  0  0  0
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 20 21  1  0  0  0  0
M  END
> <ID>
CHEBI:9620

> <NAME>
tolnaftate

> <DEFINITION>
A monothiocarbamic ester that is the methyl(3-tolyl)carbamothioate ester of 2-naphthol. A synthetic anti-fungal agent used to treat jock itch, athlete's foot and ringworm.

> <STAR>
3

> <SYNONYM>
Tolnaphthate; O-2-Naphthyl m,N-dimethylthiocarbanilate; N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide; Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester; m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester; 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate

> <IUPAC_NAME>
O-2-naphthyl methyl(3-methylphenyl)carbamothioate

> <INN>
tolnaftatum; tolnaftato; tolnaftate; tolnaftate

> <BRAND_NAME>
Tinactin; Separin

> <FORMULA>
C19H17NOS

> <MASS>
307.40900

> <MONOISOTOPIC_MASS>
307.10309

> <CHARGE>
0

> <SMILES>
CN(C(=S)Oc1ccc2ccccc2c1)c1cccc(C)c1

> <INCHI>
InChI=1S/C19H17NOS/c1-14-6-5-9-17(12-14)20(2)19(22)21-18-11-10-15-7-3-4-8-16(15)13-18/h3-13H,1-2H3

> <INCHIKEY>
FUSNMLFNXJSCDI-UHFFFAOYSA-N

> <CAS_REGISTRY_NUMBER>
2398-96-1

> <REAXYS_REGISTRY_NUMBER>
2752620

> <CHEMIDPLUS>
2398-96-1

> <DRUGBANK_ACCESSION>
DB00525

> <KEGG_DRUG_ACCESSION>
D00381

> <LINCS_ACCESSION>
LSM-5554

> <NIST_CHEMISTRY_WEBBOOK>
2398-96-1

> <WIKIPEDIA_ACCESSION>
Tolnaftate

> <PUBMED_CITATION>
20347664; 2061794; 20635527; 21565546; 22125963; 24706116; 3509341; 4568708; 5319027; 5705341; 5745067; 5847820; 5856396; 5952516; 697362

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