Ketcher 02061909472D 1 1.00000 0.00000 0 30 34 0 0 0 999 V2000 11.7536 -5.3636 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 13.4814 -5.3636 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 12.6211 -6.8650 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 14.5622 -4.1559 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 12.8408 -3.6955 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 12.6211 -5.8640 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.5881 -4.3695 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0189 -5.3636 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8861 -5.8640 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8861 -6.8650 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0189 -7.3655 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1580 -6.8650 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1580 -5.8640 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7536 -7.3655 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0189 -4.3629 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 11.7536 -8.3593 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 12.6211 -8.8598 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.6211 -9.8604 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.4814 -10.3610 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.4814 -11.3619 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.6211 -11.8624 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7536 -11.3619 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7536 -10.3610 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 15.0627 -5.0234 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 16.0435 -5.2304 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 16.3505 -6.1843 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 15.6834 -6.9316 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 14.7023 -6.7182 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 14.3956 -5.7706 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1580 -3.8624 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6 2 1 0 0 0 1 6 2 0 0 0 6 3 1 0 0 0 2 7 1 0 0 0 7 5 1 0 0 0 7 4 2 0 0 0 8 9 2 0 0 0 9 10 1 0 0 0 10 11 2 0 0 0 11 12 1 0 0 0 12 13 2 0 0 0 13 8 1 0 0 0 9 1 1 0 0 0 10 14 1 0 0 0 14 3 2 0 0 0 15 8 1 0 0 0 14 16 1 0 0 0 16 17 1 0 0 0 18 19 1 0 0 0 19 20 2 0 0 0 20 21 1 0 0 0 21 22 2 0 0 0 22 23 1 0 0 0 23 18 2 0 0 0 17 18 1 0 0 0 24 25 1 0 0 0 25 26 2 0 0 0 26 27 1 0 0 0 27 28 2 0 0 0 28 29 1 0 0 0 29 24 2 0 0 0 2 29 1 0 0 0 4 24 1 0 0 0 30 15 1 0 0 0 M END > CHEBI:143014 > ML240 > A member of the class of quinazolines that is quinazoline which is substituted at positions 2, 5 and 8 by 2-amino-1H-benzimidazol-1-yl, benzylnitrilo and methoxy groups, respectively. It is a ATP-competetive inhibitor of AAA ATPase p97, also known as valosin-containing protein (VCP). > 3 > ML240; ML-240; ML 240; 2-(2-amino-1H-benzo[d]imidazol-1-yl)-N-benzyl-8-methoxyquinazolin-4-amine; 2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine > 2-(2-amino-1H-benzimidazol-1-yl)-N-benzyl-8-methoxyquinazolin-4-amine > C23H20N6O > 396.445 > 396.16986 > 0 > N1=C(N2C(N)=NC=3C=CC=CC32)N=C(C=4C1=C(C=CC4)OC)NCC=5C=CC=CC5 > InChI=1S/C23H20N6O/c1-30-19-13-7-10-16-20(19)27-23(28-21(16)25-14-15-8-3-2-4-9-15)29-18-12-6-5-11-17(18)26-22(29)24/h2-13H,14H2,1H3,(H2,24,26)(H,25,27,28) > NHAMBLRUUJAFOY-UHFFFAOYSA-N > 1346527-98-7 > 23316025; 24878061; 25377500 $$$$