Ketcher 03271811192D 1   1.00000     0.00000     0

 19 21  0     0  0            999 V2000
    9.0607   -6.4809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.9268   -5.9809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.9268   -4.9809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    9.0607   -4.4809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.1947   -4.9809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    8.1947   -5.9809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   13.3909   -4.9809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   14.2569   -4.4809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   14.2569   -3.4809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   13.3909   -2.9809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.5249   -3.4809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   12.5249   -4.4809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    7.3287   -4.4809    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    9.0607   -3.4809    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.7929   -4.4809    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   10.7929   -6.4809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   10.7929   -7.4809    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   11.6589   -4.9809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   11.6589   -5.9809    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0     0  0
  2  3  1  0     0  0
  3  4  2  0     0  0
  4  5  1  0     0  0
  5  6  2  0     0  0
  6  1  1  0     0  0
  7  8  1  0     0  0
  8  9  2  0     0  0
  9 10  1  0     0  0
 10 11  2  0     0  0
 11 12  1  0     0  0
 12  7  2  0     0  0
  5 13  1  0     0  0
  4 14  1  0     0  0
  3 15  1  0     0  0
  2 16  1  0     0  0
 16 17  2  0     0  0
 15 18  1  0     0  0
 18 19  2  0     0  0
 16 19  1  0     0  0
 18 12  1  0     0  0
M  END
> <ID>
CHEBI:140464

> <NAME>
7,8-dihydroxyflavone

> <DEFINITION>
A dihydroxyflavone that is flavone substituted by hydroxy groups at positions 7 and 8. A dihydroxyflavone that is flavone substituted by hydroxy groups at positions 7 and 8. A naturally occurring flavonoid produced by several plants, including the weed Tridax procumbens (coalbuttons or tridax daisy) and the tree Godmania aesculifolia, In animal models, it has shown efficacy against several diseases of the nervous system, including Alzheimer's, Parkinson's, and Huntington's.

> <STAR>
3

> <SYNONYM>
7,8-dihydroxy-2-phenylchromone; 7,8-dihydroxy-2-phenyl-4-benzopyrone; 7,8-DHF

> <IUPAC_NAME>
7,8-dihydroxy-2-phenyl-4H-chromen-4-one

> <FORMULA>
C15H10O4

> <MASS>
254.238

> <MONOISOTOPIC_MASS>
254.05791

> <CHARGE>
0

> <SMILES>
C1=C2C(=C(C(=C1)O)O)OC(=CC2=O)C=3C=CC=CC3

> <INCHI>
InChI=1S/C15H10O4/c16-11-7-6-10-12(17)8-13(19-15(10)14(11)18)9-4-2-1-3-5-9/h1-8,16,18H

> <INCHIKEY>
COCYGNDCWFKTMF-UHFFFAOYSA-N

> <CAS_REGISTRY_NUMBER>
38183-03-8

> <REAXYS_REGISTRY_NUMBER>
234350

> <CHEMIDPLUS>
38183-03-8

> <WIKIPEDIA_ACCESSION>
7,8-Dihydroxyflavone

> <PUBMED_CITATION>
24503862; 26220903; 26266800; 26943953; 27019033; 27220989; 27731318; 27773794; 27824119; 27965573; 28116298; 28138113; 28256073; 28295316; 28315455; 28417199; 28541476; 28677406; 28715685; 28831019; 28950658; 29029315; 29109000; 29295929; 29500536; 29510124

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