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M  END
> <ID>
CHEBI:27470

> <NAME>
folic acid

> <DEFINITION>
An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation.

> <STAR>
3

> <SECONDARY_ID>
CHEBI:42610; CHEBI:5140; CHEBI:569217; CHEBI:24075

> <SYNONYM>
vitamin M; vitamin Be; vitamin Bc; vitamin B9; vitamin B11; pteroylmonoglutamic acid; pteroylglutamic acid; pteroyl-L-monoglutamic acid; pteroyl-L-glutamic acid; PteGlu; PGA; N-pteroyl-L-glutamic acid; N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid; Folsaeure; Folate; (2S)-2-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzamido)pentanedioic acid

> <IUPAC_NAME>
N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid

> <INN>
folic acid; acidum folicum; acido folico; acide folique

> <BRAND_NAME>
Folicet; Acfol

> <FORMULA>
C19H19N7O6

> <MASS>
441.39750

> <MONOISOTOPIC_MASS>
441.13968

> <CHARGE>
0

> <SMILES>
Nc1nc2ncc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)nc2c(=O)[nH]1

> <INCHI>
InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

> <INCHIKEY>
OVBPIULPVIDEAO-LBPRGKRZSA-N

> <BEILSTEIN_REGISTRY_NUMBER>
100781

> <CAS_REGISTRY_NUMBER>
59-30-3

> <REAXYS_REGISTRY_NUMBER>
100781

> <CHEMIDPLUS>
59-30-3

> <DRUGBANK_ACCESSION>
DB00158

> <KEGG_COMPOUND_ACCESSION>
C00504

> <KEGG_DRUG_ACCESSION>
D00070

> <KNAPSACK_ACCESSION>
C00001539

> <LINCS_ACCESSION>
LSM-5355

> <METACYC_ACCESSION>
CPD-12826

> <NIST_CHEMISTRY_WEBBOOK>
59-30-3

> <PDBECHEM_ACCESSION>
FOL

> <WIKIPEDIA_ACCESSION>
Folic_Acid

> <AGRICOLA_CITATION>
IND606960789

> <PUBMED_CITATION>
10138938; 10897644; 10958818; 11261364; 11451208; 11959400; 14387833; 15321809; 15523939; 15754725; 15797531; 15797685; 15831910; 15990733; 16093404; 16277678; 16380297; 16871332; 17784727; 19121630; 19335717; 19355913; 24650098; 33624660; 33965562; 33968971; 34207319; 34219855; 7738698; 8235383; 9040515; 9420019; 9565830; 9683174; 9781393; 9808640; 9808641; 18788725

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