Mrv0541 08211410082D 50 53 0 0 0 0 999 V2000 2.9800 -3.4564 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 2.9800 -5.9314 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 2.2540 -6.3274 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 6.5440 -3.8524 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5610 -5.9314 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2540 -4.6774 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 2.9800 -5.0734 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2540 -3.8524 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 7.2700 -3.4564 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5610 -5.0734 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 7.9630 -3.8524 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2700 -5.0734 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5440 -4.6774 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7060 -6.3274 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 7.9630 -4.6774 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1250 -6.3274 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8350 -6.3274 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.5440 -6.3274 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8180 -5.9314 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3990 -5.9314 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9800 -6.7564 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 7.2700 -5.9314 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2700 -2.6314 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0 8.6890 -3.4234 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 1.5610 -3.4234 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7060 -7.1524 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.5440 -7.1524 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6890 -2.6314 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3990 -7.5484 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5610 -4.2484 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8255 -3.4333 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 5.1099 -3.8409 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1099 -4.6659 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 4.3942 -3.4333 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2013 -2.6481 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 4.1756 -2.6481 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 2.3906 -2.8606 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.7840 -1.9324 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5692 -4.0397 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6925 -1.9325 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 7.5464 -1.1025 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8319 -0.6900 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1174 -1.1025 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4030 -0.6900 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 4.6885 -1.1025 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8295 0.1350 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.1139 -1.9325 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3982 0.1350 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9768 -0.6900 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 5.8255 -2.6083 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8 1 1 0 0 0 0 7 2 1 0 0 0 0 14 2 1 0 0 0 0 2 21 1 1 0 0 0 3 2 1 0 0 0 0 5 3 1 0 0 0 0 9 4 2 0 0 0 0 13 4 1 0 0 0 0 10 5 1 0 0 0 0 17 5 2 0 0 0 0 8 6 1 0 0 0 0 7 6 1 0 0 0 0 10 6 1 0 0 0 0 6 30 1 1 0 0 0 8 25 1 1 0 0 0 11 9 1 0 0 0 0 23 9 1 0 0 0 0 24 11 1 0 0 0 0 15 11 2 0 0 0 0 13 12 2 0 0 0 0 15 12 1 0 0 0 0 22 12 1 0 0 0 0 20 14 1 0 0 0 0 14 26 1 1 0 0 0 20 16 2 0 0 0 0 19 16 1 0 0 0 0 22 18 1 0 0 0 0 27 18 1 0 0 0 0 19 18 2 0 0 0 0 28 24 1 0 0 0 0 29 26 1 0 0 0 0 4 31 1 0 0 0 0 31 32 1 0 0 0 0 32 33 2 0 0 0 0 32 34 1 0 0 0 0 35 36 1 0 0 0 0 34 36 1 0 0 0 0 1 37 1 1 0 0 0 35 1 1 0 0 0 0 35 37 1 1 0 0 0 35 38 1 0 0 0 0 1 39 1 0 0 0 0 42 41 1 0 0 0 0 43 42 1 0 0 0 0 44 43 1 0 0 0 0 45 44 1 0 0 0 0 42 46 2 0 0 0 0 43 47 1 0 0 0 0 44 48 1 6 0 0 0 45 40 1 0 0 0 0 45 49 2 0 0 0 0 36 40 1 1 0 0 0 31 50 1 0 0 0 0 M END > CHEBI:6701 > maytansine > An organic heterotetracyclic compound and 19-membered macrocyclic lactam antibiotic originally isolated from the Ethiopian shrub Maytenus serrata but also found in other Maytenus species. It exhibits cytotoxicity against many tumour cell lines. > 3 > NSC-153858; NSC 153858; Maytansine > (4beta,5beta,11E,13E)-maytansine > maitansinum; maitansine; maitansine; maitansina > C34H46ClN3O10 > 692.19600 > 691.28717 > 0 > CO[C@@H]1\C=C\C=C(C)\Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(C)=O)[C@]2(C)O[C@H]2[C@H](C)[C@@H]2C[C@@]1(O)NC(=O)O2 > InChI=1S/C34H46ClN3O10/c1-18-11-10-12-26(45-9)34(43)17-25(46-32(42)36-34)19(2)30-33(5,48-30)27(47-31(41)20(3)37(6)21(4)39)16-28(40)38(7)23-14-22(13-18)15-24(44-8)29(23)35/h10-12,14-15,19-20,25-27,30,43H,13,16-17H2,1-9H3,(H,36,42)/b12-10+,18-11+/t19-,20+,25+,26-,27+,30+,33+,34+/m1/s1 > WKPWGQKGSOKKOO-RSFHAFMBSA-N > 35846-53-8 > 5417399 > 35846-53-8 > C10606 > D04864 > C00002351 > LMPK04000017 > Maytansine > 1241159; 20937594; 367597; 3834790; 628025 $$$$