Marvin  11270816472D          

 20 23  0  0  0  0            999 V2000
   -0.5584   -0.6763    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0916   -0.6763    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6791    0.0382    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1459    0.0382    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7293    0.6216    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4485   -1.7925    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0533   -2.3537    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8698   -3.1580    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0814   -3.4012    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.6602   -2.0357    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4766   -2.8400    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.2666   -3.1980    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.0100   -2.8400    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.1935   -2.0357    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6791   -1.3907    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1459   -1.3907    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.9819   -1.7925    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.6148   -3.4011    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.4031   -3.1579    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5866   -2.3536    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1 16  1  0  0  0  0
  1  4  1  0  0  0  0
 15  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  6  7  2  0  0  0  0
  7  8  1  0  0  0  0
  8  9  2  0  0  0  0
  6 10  1  0  0  0  0
 10 16  1  0  0  0  0
  9 11  1  0  0  0  0
 11 10  2  0  0  0  0
 11 12  1  0  0  0  0
 13 12  1  0  0  0  0
 15 14  1  0  0  0  0
 13 18  2  0  0  0  0
 14 13  1  0  0  0  0
 17 14  2  0  0  0  0
 18 19  1  0  0  0  0
 19 20  2  0  0  0  0
 17 20  1  0  0  0  0
 16 15  1  0  0  0  0
M  END
> <ID>
CHEBI:51137

> <NAME>
mianserin

> <DEFINITION>
A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

> <STAR>
3

> <SYNONYM>
1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepine

> <IUPAC_NAME>
2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine

> <INN>
mianserinum; mianserine; mianserina; mianserin

> <FORMULA>
C18H20N2

> <MASS>
264.36480

> <MONOISOTOPIC_MASS>
264.16265

> <CHARGE>
0

> <SMILES>
CN1CCN2C(C1)c1ccccc1Cc1ccccc21

> <INCHI>
InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3

> <INCHIKEY>
UEQUQVLFIPOEMF-UHFFFAOYSA-N

> <BEILSTEIN_REGISTRY_NUMBER>
755346

> <CAS_REGISTRY_NUMBER>
24219-97-4

> <CHEMIDPLUS>
24219-97-4

> <DRUGBANK_ACCESSION>
DB06148

> <LINCS_ACCESSION>
LSM-1374

> <WIKIPEDIA_ACCESSION>
Mianserin

> <PUBMED_CITATION>
18033297; 20825390

$$$$