Ketcher 05242113202D 1 1.00000 0.00000 0 35 37 0 1 0 999 V2000 18.9943 -12.5357 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 18.1283 -12.0357 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 18.1283 -11.0356 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 17.2623 -12.5357 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 17.2623 -13.5357 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 18.1283 -14.0356 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 18.1283 -15.0357 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 18.9943 -13.5357 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 19.8603 -14.0356 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 20.7264 -13.5357 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 21.5924 -14.0356 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 21.6969 -15.0301 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 22.6751 -15.2381 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 23.1751 -14.3721 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 22.5059 -13.6290 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 22.7138 -12.6508 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 19.8603 -15.0357 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 18.9943 -15.5357 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 20.7264 -15.5357 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 20.7264 -16.5357 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 16.3963 -14.0356 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 15.5302 -13.5357 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 15.5302 -12.5357 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 14.6642 -14.0356 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7506 -13.6290 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.0815 -14.3720 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.5815 -15.2381 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 14.5596 -15.0301 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 13.0815 -16.1042 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.0815 -16.1042 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5815 -15.2381 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.0815 -14.3720 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5815 -13.5060 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5815 -13.5060 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 21.6448 -13.0371 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 2 3 1 0 0 0 2 4 1 0 0 0 5 4 1 1 0 0 5 6 1 0 0 0 6 7 2 0 0 0 6 8 1 0 0 0 9 8 1 1 0 0 9 10 1 0 0 0 11 10 1 0 0 0 11 12 1 0 0 0 12 13 1 0 0 0 13 14 1 0 0 0 14 15 1 0 0 0 15 11 1 0 0 0 15 16 2 0 0 0 9 17 1 0 0 0 17 18 2 0 0 0 17 19 1 0 0 0 19 20 1 0 0 0 5 21 1 0 0 0 21 22 1 0 0 0 22 23 2 0 0 0 22 24 1 0 0 0 24 25 2 0 0 0 25 26 1 0 0 0 26 27 2 0 0 0 27 28 1 0 0 0 28 24 1 0 0 0 27 29 1 0 0 0 29 30 2 0 0 0 30 31 1 0 0 0 31 32 2 0 0 0 32 26 1 0 0 0 32 33 1 0 0 0 33 34 1 0 0 0 11 35 1 6 0 0 M END > CHEBI:172918 > PF-00835231 > A primary alcohol resulting from the cleavage of the phosphate group of the prodrug PF-07304814. It is an inhibitor of SARS-CoV-1 and -2 main protease (3CLpro) and exhibits potent in vitro antiviral activity. > 3 > PF00835231; PF-00835231; PF 00835231 > N-[(2S)-1-({(2S)-4-hydroxy-3-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide > C24H32N4O6 > 472.542 > 472.23218 > 0 > [H][C@@]1(C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)C2=CC3=C(N2)C=CC=C3OC)C(=O)CO)CCNC1=O > InChI=1S/C24H32N4O6/c1-13(2)9-18(23(32)27-17(20(30)12-29)10-14-7-8-25-22(14)31)28-24(33)19-11-15-16(26-19)5-4-6-21(15)34-3/h4-6,11,13-14,17-18,26,29H,7-10,12H2,1-3H3,(H,25,31)(H,27,32)(H,28,33)/t14-,17-,18-/m0/s1 > QDIMHKWNHMVDJB-WBAXXEDZSA-N > V2M > 32045235; 32935104; 33054210; 33515606; 33622961; 33802860 $$$$