CHEBI:75473 - etanidazole

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name etanidazole
ChEBI ID CHEBI:75473
Definition A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitro-1H-imidazol-1-yl)acetic acid with the amino group of ethanolamine. Used as a radiosensitising agent for hypoxic tumour cells.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Biological Role(s): alkylating agent
Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
radiosensitizing agent
A drug that makes increases the sensitivity of tumour cells to radiation therapy.
Related Structures
etanidazole is a Structural Derivative of
ethanolamine
Mass : 61.08312
Formula : C2H7NO
16000
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