CHEBI:64312 - memantine

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ChEBI Name memantine
ChEBI ID CHEBI:64312
Definition A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Anonymous
Secondary ChEBI IDs CHEBI:34832
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): dopaminergic agent
A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.
NMDA receptor antagonist
Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
Application(s): dopaminergic agent
A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.
antiparkinson drug
A drug used in the treatment of Parkinson's disease.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
antidepressant
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
Related Structures
memantine is a Structural Derivative of
adamantane
Mass : 136.23404
Formula : C10H16
40519
ammonia
Mass : 17.03056
Formula : H3N
16134
memantine is a Conjugate Base of
memantinium(1+)
Mass : 180.30980
Formula : C12H22N
64325
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