CHEBI:60634 - lefradafiban

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ChEBI Name lefradafiban
ChEBI ID CHEBI:60634
Definition A member of the class of pyrrolidin-2-ones that is pyrrolidin-2-one in which the 3-pro-S-hydrogen is substituted by a 2-methoxy-2-oxoethyl group, while the 5-pro-S-hydrogen is substituted by a ({4'-[N-(methoxycarbonyl)carbamimidoyl]biphenyl-4-yl}oxy)methyl group. It is an orally active prodrug of fradafiban, a figrinogen receptor antagonist.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Anonymous
Anonymous
Secondary ChEBI IDs CHEBI:60715
Supplier Information
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Roles Classification
Biological Role(s): platelet glycoprotein-IIb/IIIa receptor antagonist
Antagonist of platelet surface glycoprotein-IIb/IIIa which has a key role in hemostasis and thrombosis such as platelet adhesion and aggregation.
Application(s): prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
platelet glycoprotein-IIb/IIIa receptor antagonist
Antagonist of platelet surface glycoprotein-IIb/IIIa which has a key role in hemostasis and thrombosis such as platelet adhesion and aggregation.
Related Structures
lefradafiban is a Structural Derivative of
fradafiban
Mass : 367.39840
Formula : C20H21N3O4
73266 		methanol
Mass : 32.04186
Formula : CH4O
17790
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