CHEBI:47499 - imipramine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name imipramine
ChEBI ID CHEBI:47499
Definition A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:47498, CHEBI:5881
Supplier Information
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Roles Classification
Biological Role(s): adrenergic uptake inhibitor
Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26).
Application(s): adrenergic uptake inhibitor
Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
antidepressant
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
Related Structures
imipramine is a Functional Parent of
clomipramine
Mass : 314.85210
Formula : C19H23ClN2
47780 		trimipramine
Mass : 294.43392
Formula : C20H26N2
9738
imipramine is a Structural Derivative of
5H-dibenzo[b,f]azepine
Mass : 193.249
Formula : C14H11N
47802
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