CHEBI:44445 - nimesulide

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name nimesulide
ChEBI ID CHEBI:44445
Definition An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:44440, CHEBI:7574
Supplier Information
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Roles Classification
Biological Role(s): cyclooxygenase 2 inhibitor
A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2.
Application(s): non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
Related Structures
nimesulide is a Structural Derivative of
nitrobenzene
Mass : 123.10940
Formula : C6H5NO2
27798
sulfonic acid
Mass : 82.08008
Formula : H2O3S
29214
oxoacid
Definition : A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
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