CHEBI:42588 - 4-hydroxyphenyl retinamide

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ChEBI Name 4-hydroxyphenyl retinamide
ChEBI ID CHEBI:42588
Definition A retinoid obtained by formal condensation of the carboxy group of all-trans retinoic acid and the anilino group of 4-hydroxyaniline. Synthetic retinoid agonist. Antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Apoptotic effects appear to be mediated by a mechanism distinct from that of 'classical' retinoids.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Chemical Role(s): antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
Related Structures
4-hydroxyphenyl retinamide is a Structural Derivative of
all-trans-retinoic acid
Mass : 300.43512
Formula : C20H28O2
15367 		diterpene
Definition : A C20 terpene.
 terpene
Definition : A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH22C(CH3)CH2CH2].
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