CHEBI:3048 - benzatropine

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ChEBI Name benzatropine
ChEBI ID CHEBI:3048
Definition Tropane in which a hydrogen at position 3 is substituted by a diphenylmethoxy group (endo-isomer). An acetylcholine receptor antagonist, it is used (particularly as its methanesulphonate salt) in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:661238
Supplier Information
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
parasympatholytic
Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
Application(s): antidyskinesia agent
Any compound which can be used to treat or alleviate the symptoms of dyskinesia.
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
oneirogen
Any substance that produces or enhances dream-like states of consciousness.
antiparkinson drug
A drug used in the treatment of Parkinson's disease.
parasympatholytic
Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
Related Structures
benzatropine is a Structural Derivative of
ammonia
Mass : 17.03056
Formula : H3N
16134
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