CHEBI:143825 - ravuconazole

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ChEBI Name ravuconazole
ChEBI ID CHEBI:143825
Definition A member of the class of triazoles that is 1-butyl-1H-1,2,4-triazole in which the butyl group is substituted at positions 2, 2, and 3 by hydroxy, 2,4-difluorophenyl, and 4-(p-cyanophenyl)-1,3-thiazol-2-yl groups, respectively (the R,R stereoisomer). It exhibits antifungal activity by inhibition of 14α demethylase, an enzyme involved in sterol synthesis, resulting in lysis of the fungal cell wall and fungal cell death. (NCIO4)
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Kalpana P
Supplier Information
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Roles Classification
Biological Role(s): ergosterol biosynthesis inhibitor
Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol.
antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
EC 1.14.14.154 (sterol 14alpha-demethylase) inhibitor
Any EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of sterol 14alpha-demethylase (EC 1.14.14.154).
antileishmanial agent
An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
Application(s): antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
antileishmanial agent
An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
Related Structures
ravuconazole is a Structural Derivative of
hydrogen cyanide
Mass : 27.02530
Formula : CHN
18407
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