CHEBI:10093 - yohimbine

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ChEBI Name yohimbine
ChEBI ID CHEBI:10093
Definition An indole alkaloid with α2-adrenoceptor antagonist activity. It is produced by Corynanthe johimbe and Rauwolfia serpentina.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Biological Role(s): dopamine receptor D2 antagonist
An antagonist that binds to and deactivates the dopamine receptor D2, the main receptor for all antipsychotic drugs.
alpha-adrenergic antagonist
An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Application(s): alpha-adrenergic antagonist
An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
Related Structures
yohimbine is a Structural Derivative of
yohimbic acid
Mass : 340.41624
Formula : C20H24N2O3
35633
methanol
Mass : 32.04186
Formula : CH4O
17790
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