CHEBI:86323 - conazole antifungal agent

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name conazole antifungal agent
Definition A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties. They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:60593
Roles Classification
Biological Role(s): ergosterol biosynthesis inhibitor
Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol.
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
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