CHEBI:75282 - ergosterol biosynthesis inhibitor

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ChEBI Name ergosterol biosynthesis inhibitor
Definition Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol.
Stars This entity has been manually annotated by the ChEBI Team.
Members Of ergosterol biosynthesis inhibitor Class
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conazole antifungal agent
Definition : A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties. They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function.
isavuconazonium sulfate Mass : 814.83500
Formula : C35H36F2N8O9S2
isavuconazonium Mass : 717.76400
Formula : C35H35F2N8O5S
isavuconazole Mass : 437.46500
Formula : C22H17F2N5OS
triarimol Mass : 331.196
Formula : C17H12Cl2N2O
FR171456 Mass : 516.667
Formula : C30H44O7
Definition : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
miconazole nitrate Mass : 479.14100
Formula : C18H14Cl4N2O.HNO3 C18H15Cl4N3O4
ravuconazole Mass : 437.470
Formula : C22H17F2N5OS
Definition : A racemate comprising equimolar amounts of (R)- and (S)-myclobutanil. A sterol demethylation inhibitor, it is a widely-used agricultural fungicide.
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