CHEBI:35664 - EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor

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ChEBI Name EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
ChEBI ID CHEBI:35664
Definition Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme.
Stars This entity has been manually annotated by the ChEBI Team.
Members Of EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor Class
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mevinolinic acid Mass : 422.55490
Formula : C24H38O6
statin
Definition : Any organooxygen compound whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties.
3,3,5-trimethylcyclohexanol Mass : 142.23860
Formula : C9H18O
mevinic acid Mass : 408.529
Formula : C23H36O6
monacolin J Mass : 320.42320
Formula : C19H28O4
monacolin L Mass : 304.42380
Formula : C19H28O3
3-hydroxy-3-methylglutaric acid Mass : 162.14060
Formula : C6H10O5
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