CHEBI:101096 - ethoxzolamide

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name ethoxzolamide
ChEBI ID CHEBI:101096
Definition A sulfonamide that is 1,3-benzothiazole-2-sulfonamide which is substituted by an ethoxy group at position 6. A carbonic anhydrase inhibitor, it has been used in the treatment of glaucoma, and as a diuretic.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C9H10N2O3S2
Net Charge 0
Average Mass 258.31700
Monoisotopic Mass 258.01328
InChI InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13)
InChIKey OUZWUKMCLIBBOG-UHFFFAOYSA-N
SMILES CCOc1ccc2nc(sc2c1)S(N)(=O)=O
Roles Classification
Biological Role(s): EC 4.2.1.1 (carbonic anhydrase) inhibitor
An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H+ ions by the proximal kidney tubule.
Application(s): diuretic
An agent that promotes the excretion of urine through its effects on kidney function.
antiglaucoma drug
Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing ethoxzolamide (CHEBI:101096) has role antiglaucoma drug (CHEBI:39456)
ethoxzolamide (CHEBI:101096) has role diuretic (CHEBI:35498)
ethoxzolamide (CHEBI:101096) has role EC 4.2.1.1 (carbonic anhydrase) inhibitor (CHEBI:23018)
ethoxzolamide (CHEBI:101096) is a aromatic ether (CHEBI:35618)
ethoxzolamide (CHEBI:101096) is a benzothiazoles (CHEBI:37947)
ethoxzolamide (CHEBI:101096) is a sulfonamide (CHEBI:35358)
IUPAC Name
6-ethoxy-1,3-benzothiazole-2-sulfonamide
Synonyms Sources
6-ethoxy-2-benzothiazolesulfonamide ChemIDplus
6-Ethoxy-benzothiazole-2-sulfonic acid amide ChEMBL
6-ethoxybenzothiazole-2-sulfonamide NIST Chemistry WebBook
ethoxazolamide ChEMBL
ethoxyzolamide ChemIDplus
ETHOXZOLAMIDE ChEMBL
Manual Xrefs Databases
1089 DrugCentral
D02441 KEGG DRUG
DB00311 DrugBank
Ethoxzolamide Wikipedia
GB795174 Patent
LSM-18787 LINCS
US2868800 Patent
View more database links
Registry Numbers Types Sources
452-35-7 CAS Registry Number ChemIDplus
452-35-7 CAS Registry Number NIST Chemistry WebBook
452-35-7 CAS Registry Number KEGG DRUG
Citations Waiting for Citations Types Sources
10411484 PubMed citation ChEMBL
11087579 PubMed citation ChEMBL
11123998 PubMed citation ChEMBL
11906288 PubMed citation ChEMBL
12039560 PubMed citation ChEMBL
12617903 PubMed citation ChEMBL
12617904 PubMed citation ChEMBL
12643899 PubMed citation ChEMBL
12747790 PubMed citation ChEMBL
12747791 PubMed citation ChEMBL
14611846 PubMed citation ChEMBL
14640555 PubMed citation ChEMBL
14684333 PubMed citation ChEMBL
14971907 PubMed citation ChEMBL
15081039 PubMed citation ChEMBL
15139757 PubMed citation ChEMBL
15149691 PubMed citation ChEMBL
15454239 PubMed citation ChEMBL
15456265 PubMed citation ChEMBL
15501039 PubMed citation ChEMBL
15546717 PubMed citation ChEMBL
15603956 PubMed citation ChEMBL
15664816 PubMed citation ChEMBL
15686894 PubMed citation ChEMBL
15686895 PubMed citation ChEMBL
15686931 PubMed citation ChEMBL
15771455 PubMed citation ChEMBL
15837316 PubMed citation ChEMBL
15837325 PubMed citation ChEMBL
15905091 PubMed citation ChEMBL
15908201 PubMed citation ChEMBL
15908204 PubMed citation ChEMBL
16033263 PubMed citation ChEMBL
16039848 PubMed citation ChEMBL
16039853 PubMed citation ChEMBL
16165351 PubMed citation ChEMBL
16168653 PubMed citation ChEMBL
16302824 PubMed citation ChEMBL
16459077 PubMed citation ChEMBL
16539401 PubMed citation ChEMBL
16809036 PubMed citation ChEMBL
16942027 PubMed citation ChEMBL
17064072 PubMed citation ChEMBL
17125255 PubMed citation ChEMBL
17157501 PubMed citation ChEMBL
17228881 PubMed citation ChEMBL
17251018 PubMed citation ChEMBL
17276072 PubMed citation ChEMBL
17343373 PubMed citation ChEMBL
17475500 PubMed citation ChEMBL
17482815 PubMed citation ChEMBL
17540563 PubMed citation ChEMBL
17588751 PubMed citation ChEMBL
17646100 PubMed citation ChEMBL
17681760 PubMed citation ChEMBL
17826101 PubMed citation ChEMBL
18042384 PubMed citation ChEMBL
18242985 PubMed citation ChEMBL
18307288 PubMed citation ChEMBL
18359629 PubMed citation ChEMBL
18374572 PubMed citation ChEMBL
18513964 PubMed citation ChEMBL
2585443 PubMed citation ChEMBL
2810337 PubMed citation ChEMBL
6737424 PubMed citation ChEMBL
Last Modified
09 January 2024