Chemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on ‘small’ chemical compounds.

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Example: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine

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User Manual Learn more about the data fields in the ChEBI and data sources for ChEBI. If you are unable to access the online Google document, please use the FTP link to view our manuals.

Train Online Tutorial An online quick tour (0.5 h) and a more detailed tour (1 h) covering much of the material in the User Manual can be found on the EBI Train Online site here.

Statistics Graphs showing the growth of ChEBI, the numbers of curated, submitted and unchecked entries, the numbers of links to other resources and the sources of the information present in ChEBI



SDF files ChEBI provides its chemical structures and additional data in structure-data file (SDF) format.

Ontology files ChEBI ontology is provided in the W3C standard Web Ontology Language (OWL) and OBO formats.

Database files ChEBI is stored in a relational database and we currently provide the ChEBI tables in flat-file tab delimited format, as an Oracle binary dumps and a generic SQL dumps for MySQL and PostgreSQL database.


Entity of the month

1st March 2021

The negative health implications of obesity and its effects on mortality rates have been brought into stronger focus by the current COVID-19 crisis [1]. A recent international clinical trial published in The New England Journal for Medicine has shown that a third (35%) of obese patients treated with semaglutide (CHEBI:167574, brand name: Ozempic), lost at least a fifth of their total bodyweight within 68-weeks [2]. The results have been described as a gamechanger in the fight against obesity and the trial proves that it's possible to achieve weight loss through drugs which was previously only possible through lifestyle modifications and weight loss surgery [2].

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