# _embedded.samples[].characteristics.submission description[].text
The inflammatory response of preterm infants' intestine underlines its inability to respond to hemodynamic stress, microbes and nutrients. Recent evidence suggests that exogenous epidermal growth factor (EGF) exerts a therapeutic influence on neonatal enteropathies. However, the molecular mechanisms underlying the beneficial effects of EGF remain to be clarified. The purpose of this study was to evaluate the impact of EGF on the gene expression profiles of the developing human small and large intestine at mid-gestation in serum-free organ cultures using Illumina microarrays. Differential functional effects of EGF along the human fetal intestine [Illumina] Transcriptional profiling of small and large intestinal explants cultured in the absence (control) or in the presence of EGF (50 ng/mL).

# _embedded.samples[].characteristics.submission title[].text
Anti-Inflammatory Effects of Epidermal Growth Factor on the Immature Human Intestine

# _embedded.samples[].characteristics.sample characteristics[].text
cell line: prostate cancer cell line LNCaP; treatment protocol: treated with both caffeine and actinomycin D after treatment with caffeine

# _embedded.samples[].organization[].Name
Genomics Institute of the Novartis Research Foundation

# _embedded.samples[].characteristics.description[].text
The HCC patients had not received adjuvant chemotherapy.

# _embedded.samples[].organization[].Name
Liver Cancer Institute, Zhongshan Hospital, Fudan University;

# _embedded.samples[].characteristics.description[].text
The HCC patients had not received adjuvant chemotherapy.

# _embedded.samples[].characteristics.sample type[].text
Reference RNA pool from 20 normal livers

# _embedded.samples[].organization[].Name
Liver Cancer Institute, Zhongshan Hospital, Fudan University;

# _embedded.samples[].characteristics.description[].text
The HCC patients had not received adjuvant chemotherapy.

# _embedded.samples[].characteristics.sample type[].text
Reference RNA pool from 20 normal livers

# _embedded.samples[].organization[].Name
Liver Cancer Institute, Zhongshan Hospital, Fudan University;

# _embedded.samples[].organization[].Name
Genomics Institute of the Novartis Research Foundation

# _embedded.samples[].characteristics.description[].text
gene expression from b.End5 endothelioma cultures

# _embedded.samples[].characteristics.sample characteristics[].text
b.End5 endothelioma cultures from mouse brain microvascular cells

# _embedded.samples[].organization[].Name
Genomics Institute of the Novartis Research Foundation

# _embedded.samples[].characteristics.biosourceprovider[].text
Minoru S. H. Ko,Laboratory of Genetics,National Institute on Aging,NIH,Baltimore,MD 21224,USA, Tel. 410-558-8359. E-mail: kom@mail.nih.gov

# _embedded.samples[].characteristics.description[].text
Gene expression data from resting neutrophils from peripheral blood

# _embedded.samples[].characteristics.description[].text
Gene expression data from resting memory T cells

# _embedded.samples[].characteristics.description[].text
The HCC patients had not received adjuvant chemotherapy.

# _embedded.samples[].characteristics.sample type[].text
Reference RNA pool from 20 normal livers

# _embedded.samples[].organization[].Name
Liver Cancer Institute, Zhongshan Hospital, Fudan University;

# _embedded.samples[].characteristics.description[].text
Gene expression data from 200 mg/kg animal sacrificed on Day 29.

# _embedded.samples[].characteristics.description[].text
mRNA expression in E5 vs control cells after 2h induction