SAMEG22225

Other Group

Attributes

Type Value
Submission Reference Layer false
submission description Case-control study for the analysis of the gene expression profile of epithelial cells microdissected from normal breast tissues obtained from 17 parous and 7 nulliparous women free of breast pathology (controls), and 39 parous and 8 nulliparous women with history of breast cancer (cases). Keywords: genetic modifications Four-condition experiment: nulliparous case, nulliparous control, parous case and parous control labeled with Cy5 and Universal human reference used as a common reference labeled with Cy3. Moderated t statistic was used as the basic statistic for significance analysis; it was computed for each probe and for each contrast. False discovery rate was controlled using the Benjamini and Hochberg. All genes with P value below a threshold of 0.05 were selected as differentially expressed, maintaining the proportion of false discoveries in the selected group below the threshold value, in this case 5%. Breast 11 parous control HuII, Breast 28 parous case HuII, and Breast 62 nulliparous control HuIII excluded: raw data is missing
submission identifier GAE-GEOD-13293
submission title Parity and the genomic signature in the Human Breast

Contacts

Daniel Mailo
Gabriela Balogh
Irma Russo
Jose Russo
Julia Pereira

Organizations

Fox Chase Cancer Center
Role submitter
Fox Chase Cancer Center
Role submitter

Publications

DOI PubMedId
No DOI available 18199711

Relationships

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External Links

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BioSamples record history

Released on 2008-11-03
Last reviewed 2019-07-27