Holmes2006 - Hill's model of muscle contraction
This model is described in the article:
Abstract:
A. V. Hill's 1938 paper "The heat of shortening and the dynamic constants of muscle" is an enduring classic, presenting detailed methods, meticulous experiments, and the model of muscle contraction that now bears Hill's name. Pairing a simulation based on Hill's model with a reading of his paper allows students to follow his thought process to discover key principles of muscle physiology and gain insight into how to develop quantitative models of physiological processes. In this article, the experience of the author using this approach in a graduate biomedical engineering course is outlined, along with suggestions for adapting this approach to other audiences.
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Teaching from classic papers: Hill's model of muscle contraction.
- Holmes JW
- Advances in physiology education , 6/ 2006 , Volume 30 , Issue 2 , pages: 67-72 , PubMed ID: 16709736
- Department of Biomedical Engineering, Columbia University, New York, New York 10027, USA. jh553@columbia.edu
- A. V. Hill's 1938 paper "The heat of shortening and the dynamic constants of muscle" is an enduring classic, presenting detailed methods, meticulous experiments, and the model of muscle contraction that now bears Hill's name. Pairing a simulation based on Hill's model with a reading of his paper allows students to follow his thought process to discover key principles of muscle physiology and gain insight into how to develop quantitative models of physiological processes. In this article, the experience of the author using this approach in a graduate biomedical engineering course is outlined, along with suggestions for adapting this approach to other audiences.
Submitter of this revision: administrator
Modellers: administrator, Camille Laibe
Metadata information
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| BIOMD0000000677_urn.xml | Auto-generated SBML file with URNs | 16.28 KB | Preview | Download |
| MODEL1006230007.cps | Curated and annotated COPASI file. | 33.20 KB | Preview | Download |
| MODEL1006230007.sedml | SED-ML file for figure 1b of reference publication. | 3.20 KB | Preview | Download |
- Model originally submitted by : Camille Laibe
- Submitted: Jun 23, 2010 10:11:52 AM
- Last Modified: Mar 14, 2018 9:36:07 AM
Revisions
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Version: 3
- Submitted on: Mar 14, 2018 9:36:07 AM
- Submitted by: administrator
- With comment: Current curated version of Holmes2006_MuscleContration
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Version: 2
- Submitted on: Jun 25, 2010 1:07:23 PM
- Submitted by: Camille Laibe
- With comment: Current version of Holmes2006_MuscleContration
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Version: 1
- Submitted on: Jun 23, 2010 10:11:52 AM
- Submitted by: Camille Laibe
- With comment: Original import of Holmes2006_MuscleContration
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(added: 22 Feb 2018, 17:05:26, updated: 22 Feb 2018, 17:05:26)