MAGE-TAB Version	1.1

Investigation Title	Transcription profiling of human glial brain tumors

Experimental Design	Expression (Type I)	unknown_experiment_design_type	transcription profiling by array	
Experimental Design Term Source REF			EFO	
Experimental Design Term Accession Number	

Experimental Factor Name	
Experimental Factor Type	
Experimental Factor Term Source REF	
Experimental Factor Term Accession Number	

Person Last Name	Demeter	Bredel	
Person First Name	Janos	Markus	
Person Mid Initials	
Person Email	jdemeter@genome.stanford.edu	mbredel@stanford.edu	
Person Phone	726-0075	650-4986949	
Person Fax	723-7016	650-7361454	
Person Address	Dept. Genetics, CCSR 2255, Stanford, CA, USA, 94305	269, Stanford, CA, USA	
Person Affiliation	Stanford University	Stanford	
Person Roles	submitter	submitter	
Person Roles Term Source REF	mo	mo	
Person Roles Term Accession Number	

Quality Control Type	
Quality Control Term Source REF	
Quality Control Term Accession Number	
Replicate Type	
Replicate Term Source REF	
Replicate Term Accession Number	
Normalization Type	
Normalization Term Source REF	
Normalization Term Accession Number	

Date of Experiment	
Public Release Date	2005-10-06

PubMed ID	16204036	
Publication DOI	16204036	
Publication Author List	Bredel M , Bredel C , Juric D , Harsh GR , Vogel H , Recht LD , Sikic BI	
Publication Title	Functional Network Analysis Reveals Extended Gliomagenesis Pathway Maps  and Three Novel MYC-Interacting Genes in Human Gliomas.	
Publication Status	journal_article	
Publication Status Term Source REF	
Publication Status Term Accession Number	

Experiment Description	Gene expression profiling in 50 glial brain tumors and 4 normal brains using 42,000-feature cDNA microarrays (from total RNA). Tumors: 50 fresh-frozen glioma specimens subjected to standard WHO classification. Specimens included astrocytic [2 juvenile pilocytic astrocytomas, 1 low-grade astrocytic glioma, 1 anaplastic astrocytomas, 31 glioblastomas (of these 2 secondary glioblastomas and 2 gliosarcomas)], oligodendroglial [5 oligodendrogliomas, 3 anaplastic oligodendrogliomas], and 6 anaplastic oligoastrocytomas tumors. One tumor had been classified as glioneuronal neoplasm. Normal brain was purchased from Stratagene. Stratagene Universal Common Reference was used as reference RNA. The results provide insights into molecular mechanisms and pathways associated with gliomagenesis.

Protocol Name	URN:LSID:smd.stanford.edu:tagset.tagset\_no:25/MAGE.Protocol	
Protocol Type	feature_extraction	
Protocol Term Source REF	
Protocol Term Accession Number	
Protocol Description	Title: Feature Extraction. Description: Software and parameters for feature extraction.	
Protocol Parameters	Image Origin;Datafile type;	
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Protocol Software	
Protocol Contact	

SDRF File	E-SMDB-3152.sdrf.txt	

Term Source Name	mo	ArrayExpress	EFO	mo	
Term Source File	http://mged.sourceforge.net/ontologies/MGEDontology.php	http://www.ebi.ac.uk/arrayexpress	http://www.ebi.ac.uk/efo/	http://mged.sourceforge.net/ontologies/MGEDontology.php	
Term Source Version	

Comment[Submitted Name]	Gene expression profiling in human glial brain tumors	
Comment[MAGETAB TimeStamp_Version]	2010-08-12 13:29:50 Last Changed Rev: 13058	
Comment[ArrayExpressAccession]	E-SMDB-3152	
Comment[AEMIAMESCORE]	3	
Comment[ArrayExpressReleaseDate]	2005-10-06