Investigation Title Transcription profiling of heart ventricles from 10 week old mice heterozygous for dn-p21ras and 3 month old wild type FVB mice to study severe dilated cardiomyopathy. Comment[Submitted Name] Overexpression of dn-p21ras as a model system for severe dilated cardiomyopathy Experimental Design individual_genetic_characteristics_design co-expression_design transcription profiling by array Experimental Design Term Source REF mo EFO Comment[ArrayExpressReleaseDate] 2007-12-15 Comment[SecondaryAccession] GSE760 Comment[AEMIAMESCORE] 5 Comment[SecondaryAccession] GDS487 Comment[ArrayExpressAccession] E-GEOD-760 Comment[MAGETAB TimeStamp_Version] 2011-01-23 01:12:47 Last Changed Rev: 14857 Experimental Factor Name genotype Experimental Factor Type genotype Experimental Factor Term Source REF Person Last Name Schinke Person First Name Martina Person Mid Initials Person Email mschinke@cgr.harvard.edu Person Phone Person Fax Person Address Cardiogenomics, Bauer Center for Genomic Research, Harvard University, 7 Divinity Ave, Cambridge, 02138, USA Person Affiliation Harvard University Person Roles submitter Person Roles Term Source REF Quality Control Type Quality Control Term Source REF Replicate Type Replicate Term Source REF Normalization Type Normalization Term Source REF Date of Experiment Public Release Date 2007-12-15 PubMed ID Publication DOI Publication Author List Publication Title Publication Status Publication Status Term Source REF Experiment Description Mice heterozygous for dn-p21 littermates were sacrificed at 10 weeks of age. Ventricles were isolated and snap-frozen in liquid nitrogen. Use 3 month old FVB Females as controls. [GSM2334, GSM2335, GSM2336]; Read more at http://cardiogenomics.med.harvard.edu/groups/proj1/pages/ras_home.html Protocol Name Affymetrix:Protocol:Hybridization-Unknown P-AFFY-6 Protocol Type hybridization feature_extraction Protocol Description Title: Affymetrix Generic Hybridization. Description: Title: Affymetrix CEL analysis. Description: Protocol Parameters Protocol Hardware Protocol Software MicroArraySuite 5.0 MicroArraySuite 5.0 Protocol Contact Protocol Term Source REF mo SDRF File E-GEOD-760.sdrf.txt Term Source Name EFO The MGED Ontology NCI_thesaurus ArrayExpress mo EFO Term Source File http://www.ebi.ac.uk/efo/ http://mged.sourceforge.net/ontologies/MGEDontology.php ncithesaurus.obo.alt http://www.ebi.ac.uk/arrayexpress http://mged.sourceforge.net/ontologies/MGEDontology.php http://www.ebi.ac.uk/efo/ Term Source Version Comment[AEExperimentType] transcription profiling by array