E-TABM-991 - Transcription profiling by array of mouse CD8+ naive T cells from mice expressing normal IL-7R or conditional IL-7R alpha switched on or off for different amounts of time
Submitted on 4 May 2010, released on 20 December 2010, last updated on 2 May 2014
The transcriptional profile of CD8+ naive T cells was compared from F5 transgenic mice expressing normal IL-7R or a conditional IL-7R alpha that was either switched on, or switched off for different amounts of time.
transcription profiling by array, co-expression, strain or line
IL-7 determines T cell fitness by distinct mechanisms at different signal strengths. Claire Pearson, Ana Silva, Manoj Saini, Benedict Seddon.