E-MTAB-8321 - RNA-seq data from healthy and DMD human cells, along skeletal muscle differentiation from induced pluripotent stem cells
Last updated on 18 August 2020, released on 5 October 2020
3 healthy cells - 3 DMD cells - 7 time points (tissue-derived myoblasts, tissue-derived myotubes, hiPSCs, Day 3 of differentiation, Day 10 of differentiation, Day 17 of differentiation, Day 25 of differentiation) - 1 replicate per cell line for the tissue-derived samples and 3 biological replicates per cell line for the hiPSC-derived samples.
RNA-seq of coding RNA, development or differentiation design, genetic modification design, time series design
Myogenesis modelled by human pluripotent stem cells uncovers Duchenne muscular dystrophy phenotypes prior to skeletal muscle commitment. Virginie Mournetas, Emmanuelle Massouridès, Jean-Baptiste Dupont, Etienne Kornobis, Hélène Polvèche, Margot Jarrige, Maxime Gosselin; Spiros D. Garbis; Dariusz C. Górecki; Christian Pinset.