E-MTAB-8149 - Microarray transcriptome profiling of atopic dermatitis and psoriasis patients compared to healthy volunteers
Submitted on 11 February 2016, last updated on 10 September 2019, released on 11 September 2019
Characteization host-microbiome interactions in patients with allergic (model: atopic dermatitis) and autoimmune (model: psoriasis) diseases by integration of microarray transcriptome data with 16S microbial profiling. 6mm punch biopsies were collected from the skin of atopic dermatitis and psoriasis patients alongside healthy volunteers, and subjected to analysis using Affymetrix Human Gene ST 2.1 arrays.
transcription profiling by array, case control design, disease state design
Microbe-host interplay in atopic dermatitis and psoriasis. Nanna Fyhrquist, PhD, Gareth Muirhead, MSc, Stefanie Prast-Nielsen, PhD, Marine Jeanmougin, MSc, Peter Olah, PhD, Tiina Skoog, PhD, Gerome Jules-Clement, BSc, Micha Feld, PhD, Mauricio Barrientos-Somarribas, MSc, Hanna Sinkko, PhD, Ellen van den Bogaard, PhD, Patrick Zeeuwen, PhD, Gijs Ricken, PhD, Joost Schalkwijk, PhD, Tom Ederveen, PhD, Walter Däubener, PhD, Silvia Kathrin Eller, PhD, Helen Alexander, MD, Davide Pennino, PhD, Sari Suomela, MD, PhD, Ioannis Tessas, MD, PhD, Emilia Lybeck, MD, Anna M. Baran, MSc, Hamid Darban, MSc, Roopesh Singh Gangwar, PhD, Ulrich Gerstel, MSc, Katharina Jahn, MSc , Piia Karisola, PhD, Lee Yan, MSc, Britta Hansmann, MSc, Shintaro Katayama, PhD, Stephan Meller, PhD, Max Bylesjö, PhD, Philippe Hupé, PhD, Francesca Levi-Schaffer, PhD, Dario Greco, PhD, Annamari Ranki, MD, PhD, Jens M. Schröder, PhD, Jonathan Barker, MD, PhD, Juha Kere, MD, PhD, Sophia Tsoka, PhD, Antti Lauerma, MD, PhD, Vassili Soumelis, MD, PhD, Frank O. Nestle, PhD, Bernhard Homey, MD, PhD, Björn Andersson, PhD, Harri Alenius, PhD.