E-MTAB-785 - ChIP-Seq of human breast cancer cell lines MCF-7 in the absence of hormone and after Estradiol treatment with antibody against Estrogen Receptor cofactors SRC1, SRC2, SRC3, CBP and p300

Status
Released on 25 October 2011, last updated on 2 May 2014
Organism
Homo sapiens
Samples (1)
Protocols (6)
Description
The Estrogen Receptor cofactors SRC1 (NCOA1, KAT13A), SRC2 (NCOA2, GRIP1, TIF2, KAT13C) , SRC3 (NCOA3, AIB1, KAT13B, Rac3) , CBP and p300 are assessed for their genome-wide chromatin binding capacities in the breast cancer cell line MCF7. To determine the Estrogen Receptor dependency of interactions, experiments were performed in the absence of hormone and after Estradiol treatment. In addition, the data were compared with Estrogen Receptor ChIP-seq data from the same timepoint of Estradiol treatment.
Experiment types
ChIP-seq, binding site identification, compound treatment, replicate
Contact
Citations
Oestrogen receptor-co-factor-chromatin specificity in the transcriptional regulation of breast cancer. Zwart W, Theodorou V, Kok M, Canisius S, Linn S, Carroll JS. EMBO J  (2011), PMID:22002538
Oestrogen receptor-co-factor-chromatin specificity in the transcriptional regulation of breast cancer. Zwart W, Theodorou V, Kok M, Canisius S, Linn S, Carroll JS. EMBO J  (2011)
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-MTAB-785.idf.txt
Sample and data relationshipE-MTAB-785.sdrf.txt
Processed data (1)E-MTAB-785.processed.1.zip
Links