E-MTAB-7765 - RNAseq of the small intestine of mice 6 days after they were transplanted with either wildtype allogeneic T cells or glucocorticoid-resistant allogeneic T cells (mouse model of acute graft-versus-host disease

Status
Submitted on 14 August 2017, last updated on 12 March 2019, released on 12 March 2019
Organism
Mus musculus
Samples (10)
Protocols (8)
Description
Given that mice transplanted with glucocorticoid-resistant T cells display more severe disease symptoms, the idea was that an RNA-seq comparison between mice transplanted with either wildtype or glucocorticoid-resistant T cells could yield genes involved in disease progression and potential therapeutic targets.
Experiment types
RNA-seq of coding RNA, genetic modification design
Contact
Citation
Glucocorticoid resistance of allogeneic T cells alters the gene expression profile in the inflamed small intestine of mice suffering from acute graft-versus-host disease. Hu Li, Tina K. Kaiser, Marina Borschiwer, Hanibal Bohnenberger, Fred Lühder, Lutz Walter, Ralf Dressel, Sebastiaan H. Meijsing and Holger M. Reichardt.
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-MTAB-7765.idf.txt
Sample and data relationshipE-MTAB-7765.sdrf.txt
Processed data (1)E-MTAB-7765.processed.1.zip
Links