E-MTAB-7107 - RNAseq of murine primary bone marrow cells transformed by an inducible Hoxa9-ER: time-course

Status
Submitted on 31 July 2018, last updated on 13 April 2019, released on 13 April 2019
Organism
Mus musculus
Samples (6)
Protocols (4)
Description
Relative overexpression of HOXA9 is a key feature of aggressive AML (acute myeloid leukemia). Hoxa9 responsive genes were identified by nascent RNA sequencing (4-thio-uridine labeled RNA - sequencing) in samples of primary hematopoietic precursor cells from mice transformed by an tamoxifen inducible version of Hoxa9 (Hoxa9-ER). Samples were generated in the presence of active Hoxa9 (0h) and in a time series after Hoxa9 was inactivated at 8h, 16h, 24h, 48h, and 72h.
Experiment types
RNA-seq of coding RNA, time series design
Contact
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-MTAB-7107.idf.txt
Sample and data relationshipE-MTAB-7107.sdrf.txt
Links