E-MTAB-7103 - RNA-seq of equine and canine mammary stem cells treated with DMBA

Status
Submitted on 30 March 2017, last updated on 1 August 2018, released on 31 August 2018
Organism
Canis lupus familiaris, Equus caballus
Samples (12)
Protocols (4)
Description
Whereas canines are susceptible to mammary cancer at a frequency similar to humans, equines are largely resistant to the disease. We treated mammary stem cells from both species with the chemical carcinogen, DMBA, and found that equine cells are significantly more susceptible to treatment. These RNA-seq results represent samples from three individuals of dogs and horses in order to reveal transcriptional differences in response to treatment that may explain the phenotypic differences we observed.
Experiment types
RNA-seq of coding RNA, compound treatment design
Contact
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-MTAB-7103.idf.txt
Sample and data relationshipE-MTAB-7103.sdrf.txt
Links