E-MTAB-6505 - Monocyte-derived IL-1 and IL-6 are differentially required for cytokine release syndrome and neurotoxicity by CAR-T cells

Status
Submitted on 29 November 2017, last updated on 24 May 2018, released on 24 May 2018
Organism
Homo sapiens
Samples (4)
Protocols (4)
Description
Single-cell transcriptome profiling using a 3' droplet-based platform (Chromium,10x Genomics) of human CD45+ leukocytes isolated from leukemic HuSGM3 mice infused with CD19.28z CAR-T cells, two days after cytokine release syndrome (CRS) onset and 5 days later.
Experiment type
RNA-seq of coding RNA from single cells 
Contacts
Citation
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-MTAB-6505.idf.txt
Sample and data relationshipE-MTAB-6505.sdrf.txt
Links