E-MTAB-6352 - RNA-seq of Staphylococcus aureus and Staphylococcus aureus challenged with squalene compared to control growth
Submitted on 30 September 2016, last updated on 6 March 2018, released on 30 June 2018
Staphylococcus aureus, Staphylococcus epidermidis
Squalene makes up 12 % of human skin surface lipids, however little is known about its affects on the host skin microbiome. Here we tested the effect of squalene on genetic regulation of staphylococci, showing that it profoundly affects expression virulence or colonisation determinants, and of iron uptake systems.
RNA-seq of coding RNA, compound treatment design, growth condition design, strain or line design