E-MTAB-5859 - Resistant and susceptible chicken lines show distinctive responses to Newcastle disease virus infection in the lung transcriptome

Submitted on 27 March 2014, last updated on 29 September 2017, released on 14 October 2017
Gallus gallus
Samples (48)
Protocols (8)
This study aimed to characterize differential responses between the relatively resistant (Fayoumi) and susceptible (Leghorn) chicken lines when challenged with a high titered lentogenic Newcastle Disease Virus (NDV) strain via the eyes and nostrils at three weeks of age. The lung was collected from challenged and non-challenged birds from each line at 2, 6, and 10 days-post-infection (dpi). High quality RNA was isolated, used for cDNA library construction, and sequenced on the HiSeq2500.
Experiment types
RNA-seq of coding RNA, case control design, disease state design, sex design, strain or line design, time series design
Exp. designProtocolsVariablesProcessedSeq. reads
Investigation descriptionE-MTAB-5859.idf.txt
Sample and data relationshipE-MTAB-5859.sdrf.txt