E-MTAB-5859 - Resistant and susceptible chicken lines show distinctive responses to Newcastle disease virus infection in the lung transcriptome
Submitted on 27 March 2014, last updated on 29 September 2017, released on 14 October 2017
This study aimed to characterize differential responses between the relatively resistant (Fayoumi) and susceptible (Leghorn) chicken lines when challenged with a high titered lentogenic Newcastle Disease Virus (NDV) strain via the eyes and nostrils at three weeks of age. The lung was collected from challenged and non-challenged birds from each line at 2, 6, and 10 days-post-infection (dpi). High quality RNA was isolated, used for cDNA library construction, and sequenced on the HiSeq2500.
RNA-seq of coding RNA, case control design, disease state design, sex design, strain or line design, time series design