E-MTAB-5614 - RNA-seq of blood taken from patients suffering from sleeping sickness and infected with Trypanosoma brucei rhodesiense
Last updated on 8 June 2018, released on 18 June 2018
Shotgun sequencing of sleeping sickness patient blood. WARNING: these results cannot be compared with those from trypanosome poly(A)+ mRNA, because the poly(A) selection introduces substantial bias, including loss of long mRNAs. Details will appear in the publication. These are additional sequencing runs that match some from E-MTAB-5293
RNA-seq of coding RNA, cell type comparison design, disease state design
Transcriptomes of Trypanosoma brucei rhodesiense from sleeping sickness patients, rodents and culture: Effects of strain, growth conditions and RNA preparation methods. Mulindwa J, Leiss K, Ibberson D, Kamanyi Marucha K, Helbig C, Melo do Nascimento L,Silvester E, Matthews K, Matovu E, Enyaru J, Clayton C.