E-MTAB-5557 - Time course RNA-seq of Mycobacterium tuberculosis exposed to nitric oxide

Status
Submitted on 22 February 2017, last updated on 29 August 2017, released on 29 August 2017
Organism
Mycobacterium tuberculosis H37Rv
Samples (15)
Protocols (7)
Description
Mycobacterium tuberculosis is an intracellular human pathogen with the ability to resist and adapt to many adverse conditions it encounters upon infection. Among these, overcoming the production of nitric oxide by macrophages could be key for M. tuberculosis success. We have challenged M. tuberculosis with a sub-lethal concentration of nitric oxide and followed the transcriptomic response through RNA-seq for 48 hours.
Experiment types
RNA-seq of coding RNA, stimulus or stress design
Contact
Citation
Delayed effects of transcriptional responses in Mycobacterium tuberculosis exposed to nitric oxide suggest other mechanisms involved in survival. Cortes T, Schubert OT, Banaei-Esfahani A, Collins BC, Aebersold R, Young DB. Scientific Reports 7(1):8208 (2017), PMID:28811595
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-MTAB-5557.idf.txt
Sample and data relationshipE-MTAB-5557.sdrf.txt
Links