E-MTAB-5368 - Phosphoglycerate dehydrogenase causes electron transport chain defect via impaired heme synthesis: RNA sequencing

Status
Submitted on 16 November 2016, last updated on 29 August 2018, released on 29 August 2018
Organism
Homo sapiens
Samples (6)
Protocols (3)
Description
Given the prominent angiogenic impairment in PHGDHECKO mice and the proliferation defect of PHGDHKD ECs, which could not fully be explained by a decreased one carbon metabolism pool, together with the observed impairment of mitochondrial homeostasis and reduced respiration in PHGDHKD ECs, we performed an RNA-seq analysis of control and PHGDHKD ECs.
Experiment types
RNA-seq of coding RNA, case control design
Contact
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-MTAB-5368.idf.txt
Sample and data relationshipE-MTAB-5368.sdrf.txt
Links