E-MTAB-5189 - Transcriptional profiling of Setd5 heterozygous and knockout mouse embryonic stem cells
Submitted on 20 September 2016, released on 13 December 2016, last updated on 15 December 2016
SET-domain containing proteins play a vital role in regulating gene expression during development through modifications in chromatin structure. To study molecular function of SET domain containing 5 (Setd5), we assessed global changes in the mouse embryonic stem cell transcriptome when Setd5 gene is knocked out.
RNA-seq of coding RNA, genetic modification design