E-MTAB-4920 - RNA-seq of sh2-H2AFJ and sh-NoTarget in WI-38hTERT cells induced into senescence by etoposide
Status | Last updated on 11 July 2016, released on 21 July 2016 | ||||||||||
Organism | Homo sapiens | ||||||||||
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Description | Study the role of H2A.J in gene expression in senescent human fibroblasts by comparing RNA-seq of WI-38hTERT fibroblasts expressing either an sh2-H2AFJ or sh-NoTarget RNAs. Senescence was induced by treating cells with 20 M etoposide for 2 weeks followed by one further week of incubation without etoposide. 3 biological replicates of sh2-H2AFJ and sh-NoTarget were sequenced. | ||||||||||
Experiment types | RNA-seq of coding RNA, genetic modification design, stimulus or stress design | ||||||||||
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MINSEQE |
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