E-MTAB-4691 - Transcriptional response of Pseudomonas aeruginosa to treatment with the antibacterial compound SPI031

Status
Submitted on 2 December 2014, last updated on 10 May 2016, released on 19 May 2016
Organism
Pseudomonas aeruginosa UCBPP-PA14
Samples (3)
Protocols (7)
Description
A transcriptome analysis was performed using RNA sequencing to uncover the cellular responses of Pseudomonas aeruginosa PA14 to SPI031. To assess the direct effects of the compound on cellular processes, the transcription profile was determined from cells treated for 5 min with a sub-inhibitory concentration of SPI031 (0.2x MIC).
Experiment type
RNA-seq of coding RNA 
Contacts
Citations
Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa. Gerits E, Blommaert E, Lippell A, ONeill AJ, Weytjens B, De Maeyer D, Fierro AC, Marchal K, Marchand A, Chaltin P, Spincemaille P, De Brucker K, Thevissen K, Cammue BP, Swings T, Liebens V, Fauvart M, Verstraeten N, Michiels J. :e0155139 (2016), PMID:27167126
Elucidation of the mode of action of a new antibacterial compound active against Staphylococcus aureus and Pseudomonas aeruginosa. Evelien Gerits, Eline Blommaert, Anna Lippell, Alex J. ONeill, Bram Weytjens, Dries De Maeyer, Ana Carolina Elisa Fierro Gutierrez, Kathleen Marchal, Arnaud Marchand, Patrick Chaltin, Katrijn De Brucker, Karin Thevissen, Bruno P.A. Cammue, Toon Swings, Veerle Liebens, Maarten Fauvart, Natalie Verstraeten, Jan Michiels.
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-MTAB-4691.idf.txt
Sample and data relationshipE-MTAB-4691.sdrf.txt
Links