E-MTAB-4117 - Gene expression profiles of 25 Drosophila melanogaster mutation accumulation lines
Submitted on 1 November 2011, last updated on 26 May 2016, released on 26 May 2016
25 lines are maintained with 10 females and 10 males to accumulate mutations from a single inbred strain DGRP_360. Mutations are allowed to accumulate for 60 generations. At generation 60, 10 3-5 day old adult flies, sex separately, are pooled and whole body RNA are extracted and profiled for gene expression. This data set allows estimation of mutational variance in gene expression.
transcription profiling by array, strain or line design
Spontaneous mutations and the origin and maintenance of quantitative genetic variation. Huang W, Lyman RF, Lyman RA, Carbone MA, Harbison ST, Magwire MM, Mackay TF. :None (2016), Europe PMC 27213517