E-MTAB-3813 - GFRA3 promoter methylation is associated with decreased postoperative survival in gastric cancer
Submitted on 18 July 2011, last updated on 12 August 2015, released on 31 October 2015
Biopsies from 24 gastric adenocarcinomas and adjacent normal gastric mucosa were analyzed for from 24 patients following surgical resection of the tumor. Genome-wide DNA methylation profiling of the tumor and matched non-cancerous mucosa was performed and compared to previously performed gene expression, survival and clinicopathological parametres.
methylation profiling by array, case control design
GFRA3 promoter methylation may be associated with decreased postoperative survival in gastric cancer. Eftang LL, Klajic J, Kristensen VN, Tost J, Esbensen QY, Blom GP, Bukholm IR, Bukholm G. :225 (2016), PMID:26984265